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In embryofetal developmental studies, clozaril had no effects on maternal parameters, litter sizes, or fetal parameters when administered orally to pregnant rats and rabbits during the period of organogenesis at doses up to 0.

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This medication may rarely make your blood sugar risewhich can cause or worsen diabetesTell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urinationIf you already have diabetescheck your blood sugar regularly as directed and share the results with your doctorYour doctor may need to adjust your diabetes medicationexercise programor diet.

UsesFor the treatment of severely ill patients with schizophrenia who fail to respond adequately to standard antipsychotic treatmentTo reduce the risk of recurrent suicidal behavior in patients with schizophrenia or schizoaffective disorderwho are judged to be at chronic risk for re-experiencing suicidal behaviorbased on history and recent clinical state.

Since Clozaril may be associated with thromboembolismimmobilisation of patients should be avoided.

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you should tell your doctor immediately if you experience any signs of infection, such as flu-like symptoms, high temperature fever , sore throat or inflammation of the lining of the mouth stomatitis , while taking clozaril.

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